Prognostic factors in colorectal cancer

Aim: to evaluate prognostic factors in colorectal cancer. Material and methods: published data (publications PubMed, Scopus, eLIBRARY databases) own results of treatment 47 patients with T2-4N0-2M0 colon cancer 2017–2018. The following were studied: metastasis regional lymph nodes, tumor site, CEA level, KRAS BRAF mutation status, microsatellite instability, MUSASHI2, p53, VEGF. Results: a correlation between progression the status nodes demonstrated significant differences (p = 0.038): N0, risk was 3.8%, N1 — 14.9%, N2 43.6%. Statistical processing did not reveal groups without generalization by their age, gender, type node dissection, T stage, differentiation adenocarcinoma, levels CEA, mutations KRAS, MSI, We used these determine biological features tumor, its aggressiveness approaches. Conclusions: remains main factor determining prognosis medical therapy appointment. Molecular genetic are currently great importance for tactics personalized treatment.